Gynecomastia :: science

Gynecomastia Definition Gynecomastia is a super C disease of the male breast where there is a benign glandular gush of that breast at some time in the males life. It commonly consists of the appearance of a flat pad of glandular tissue down the stairs a nipple which becomes tender at the same time. The development may be unilateral or bilateral. There is rarely a move growth of the breast tissue ordinarily the process is of brief time and stops short of the production of permanent enlargement of the breast. Causes A salient number of patients who suffer from this disease have a disturbance in the proper dimension of androgen and oestrogen levels. The conventionality ratio of the both hormones in plasma is approximately 1001. The etiology of gynecomastia in patients with a known documented cause appears to be related to increased estrogen stimulation, decreased testosterone levels, or some alteration of the estrogens and androgen so that the androgen-estrogen ratio is decr eased(Williams 373). From this information it was discovered that there is in addition a set about ratio of weaker adrenal androgens (delta 4-androstenedione and dehydroepiandrosterone) found in youths with this disease. It was once believed that there was an dissymmetry in the ratios of testosterone to estrogen or estradiol, but this is now know to be untrue. There are three areas the can be attributed to the cause of gynecomastia physiologic, pathological and pharmacologic. Enlargement of the male breast can be a normal physiologic phenomenon at certain stages of life or the result of some(prenominal) pathologic states.(Isselbacher, 2037) In the case of physiologic gynecomastia the disease can materialize in a newborn baby, at puberty or at any time in a mans life. In the newborn, transient enlargement of the breast is due to the action of maternal and/or placental estrogens. The enlargement usually disappears within a few weeks. Adolescent gynecomastia is common during pube rty with the onset at the median age of 14. It is often asymmetrical and ofttimes tender. It regresses so that by the age of 20 only a minor number of men have palpable vestiges of gynecomastia in one or both the breasts. Gynecomastia of aging also occurs in otherwise healthy men. forty percent or more of aged men have gynecomastia. wiz explanation is the increase in age in the conversion of androgens to estrogens in extra- glandular tissues. Drug therapy and abnormal liver functioning can also be causes of gynecomastia in older men.